Monday, December 12, 2016

The light in Alzheimer’s disease – new therapy – Interfax

a Group of scientists from Massachusetts proves that shines a strobe light into the eyes of rodents promotes protective cells of brain neurons (the so-called mikroglej) for a natural “pożerania” harmful protein beta-amyloid that accumulates in the brain of a person suffering from Alzheimer’s disease.

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Ideal temp is 40 flashes per second is barely perceptible flickering four times faster than a strobe light in disco clubs.
the Americans claim that their research is quite promising, which should be tested with the participation of the people.
already Filed the application to obtain permission to create the company that would develop new technologies for the FDA – the Agency for control of drugs.

the Accumulation of beta-amyloid is one of the changes observed in the brain of patients. Protein is a “stick” to each other, forming a tile and it is currently believed that the cause of death of nerve cells and related memory loss.
Scientists are looking for ways to pharmacologically get rid of beta-amyloid, but while testing the therapy denied.

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Dr. Li-Huei Tsai and colleagues at mit believe they have found another way – light treatment. The details of the work publishes the journal “Nature”.

the Mouse that felt the Americans were genetically modified to over time has evolved in the brain damage of the type alzheimerowskiego.

Rodents were placed in front of a flashing light in an hour. It turned out that in their brain (the visual cortex) there was a significant reduction of beta-amyloid within the next 12 to 24 hours. An hour of daily therapy used in the course of the week, led to a further reduction of the protein.


Direct the “light” part of the brain that “does” memory – hipokampu – called also in this structure, a decrease in the number of beta-amyloid.
Scientists say that the light waves stimulate the immune cells, that is referred to mikroglej.

- Mikroglej is scavengers. Its cells eat harmful or dangerous pathogens – in this case, beta-amyloid. It is hoped that clearing the brain of deposits of beta-amyloid will halt the creation of consecutive tiles and stop the development of Alzheimer’s disease, say researchers.

- We are optimistic – he said in interview bi-BI-si Dr. Tsai.
Scientists believe that in the future people will be able to wear special glasses or sit in front of the device emitującym light in the treatment stroboskopowej. For the patient it should be completely painless and non-invasive.
- We can use “soft” the light is very low intensity. His flickering almost imperceptibly.

will Not, therefore, robbery padaczkowego [sensitive people blink, for example, the TV screen may cause a seizure, before they warn sometimes the subtitles are displayed before the release of the film], even a person vulnerable – explain.

Dr. David Reynolds of the British Society for Patients with Alzheimer’s disease, said bi-bi-si: – Research, as valuable at least because to identify new processes involved in the development of the disease. Mouse is not the same as humans. Especially that they don’t get sick on the classic equivalent of human Alzheimer’s disease, but these studies are important because they give new tips for future therapy.

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